RAF Typhoon FGR4s have joined forces with France's air force in a coordinated attack targeting an hidden munitions depot in Syrian territory used by the Daesh militant organization, according to the UK's MoD.
The location, located using intelligence, was believed to be storing arms and explosives, the release indicated, and was situated in mountains just above the historic site of Palmyra in central Syria.
"The RAF jets used precision-guided Paveway IV munitions to hit a several approach shafts down to the depot... initial indications are that the target was engaged successfully," the MoD said.
There was no evidence of any harm to civilians in the operation on Saturday evening and all the aircraft returned to base without incident, the defence officials confirmed.
The Typhoon FGR4s were supported by a Voyager aerial refuelling aircraft.
IS - referred to as the so-called Islamic State - imposed militant control over large swathes of Iraq and Syria until 2019.
"This operation underscores our UK leadership, and commitment to work closely with our partners, to stamp out any revival of Daesh and their violent and radical beliefs in the Middle East," the British Defence Secretary the minister remarked.
British military aircraft have conducted patrols over Syria to "deter any attempted resurgence" of the group subsequent to its military defeat at the Baghuz confrontation in 2019, the authorities noted.
"I must thank all the members of British forces involved in this mission for their professionalism and their courage," he added. "They were among a great many UK service members stationed over the festive period. This mission, to remove terrorist threats who pose a risk to our way of life, demonstrates how UK forces are prepared to act, all year round, ensuring Britain's security at home and influential overseas."
Last December, the US military carried out what it called a "major assault" against IS targets in Syria, after an assault resulted in the deaths of two US troops and a civilian interpreter in the Palmyra area.
The UN estimates Daesh still boasts between 5,000 and 7,000 militants in Iraq and Syria.